Welcome to the Baym Lab at Harvard Medical School, started in July 2017!
Antibiotic resistance is one of the defining public health threats of our time. Every time a new antibiotic has been introduced, resistance rapidly follows. We study how resistance evolves with the goal of making practical interventions that take into account, and even anticipates, pathogen evolution.
Our research ranges from basic evolutionary biology and bacteriology to analysis of clinical sequencing data to technology development.
Or, to describe what we do in Up Goer Five terms:
Our research is supported by the David and Lucile Packard Foundation, the Sloan Foundation, the Pew Charitable Trusts, and the NIH NIGMS.
May 2021: Siân's collaboration with the Balskus lab, The gut bacterial natural product colibactin triggers induction of latent viruses in diverse bacteria, is posted as a preprint
April 2021: Karel's paper: Simplitigs as an efficient and scalable representation of de Bruijn graphs, is published in Genome Biology!
April 2021:Cristina's preprint posted: Decreased thermal tolerance as a trade-off of antibiotic resistance
March 2021: Michael's collaboration with Lee Kennedy-Shaffer and Bill Hanage, Perfect as the enemy of good: tracing transmissions with low-sensitivity tests to mitigate SARS-CoV-2 outbreaks, is published in The Lancet Microbe
March 2021: Michael has received a 2021 A. Clifford Barger Excellence in Mentoring Award from Harvard Medical School
February 2021: Ellie passed her qualifying exams. Way to be qualified, Ellie!
October 2020: Jasmijn is awarded the 2020 BioSB Young Investigator Award! Congratulations Jasmijn!!
October 2020: Arya joined the lab as a PhD student!
October 2020: Michael's collaboration with the Zhang Lab at Rice, Metastable hybridization-based DNA information storage to allow rapid and permanent erasure, is published in Nature Communications
August 2020: Ellie joined the lab as a PhD student!
July 2020:Siân and Natalia's preprint posted: Prophage-encoded phage defence proteins with cognate self-immunity
June 2020: The lab has been awarded a Pew Biomedical Scholarship for 2020-2024! 🎉🎉🎉
June 2020: Victoria and Siân's paper, Forensic microbial system for high-resolution object provenance, is published in Science!
May 9, 2020: Ellie helps the NC Dinos (NC 다이노스) throw out the first pitch.
February 2020: The lab has been awarded a Sloan Research Fellowship for 2020-2022! 🎉🎉🎉
February 2020: Karel's paper, Rapid inference of antibiotic resistance and susceptibility by genomic neighbour typing is published in Nature Microbiology!