Welcome to the Baym Lab at Harvard Medical School, started in July 2017!
Antibiotic resistance is one of the defining public health threats of our time. Every time a new antibiotic has been introduced, resistance rapidly follows. We study how resistance evolves with the goal of making practical interventions that take into account, and even anticipates, pathogen evolution. This relies on both experimental recapitulation of the process of resistance evolution as well as the study of genomic data from real-world infections.
More broadly, antibiotic resistance provides an excellent model system for evolution. In a sense, we as a society have been performing a directed evolution experiment in pathogens on a worldwide scale. Only now, with rapid sequencing, is the technology becoming available to understand the results.
October 2018: The lab has been awarded a 2018-2023 Packard Fellowship!
August 28, 2018: Karel's preprint posted: Lineage calling can identify antibiotic resistant clones within minutes
September 2018: Eve joined the lab as a master's student
September 2018: Michael speaks at the Southern California Microbiome Symposium
September 2018: Michael speaks at Lake Arrowhead Microbial Genomics, Siân and Karel present posters
September 2018: Cristina speaks at ISME in Germany
August 2018: Anurag joined the lab as a PhD student
July 2018: Natalia joined the lab as a PhD student
July 2018: Michael speaks at Microbial Stress Response GRC
May 2018: Isabel joined the lab as a summer undergrad
April 2018: Michael speaks at the Harvard MSI Symposium
April 2018: Simone joined the lab as a master's student
April 2018: Siân joined the lab as a postdoc
March 2018: Victoria joined the lab as a technician
February 2018: Scott joined the lab as a visiting postdoc
February 8, 2018: Cristina's preprint posted: Stronger connectivity of the resident gut microbiome lends resistance to invading bacteria
September 2017: Cristina joined the lab
August 2017: Michael speaks at the Microbial Darwinian Medicine Workshop
July 2017: The lab has started! Karel joins the lab as a joint postdoc with the Hanage Lab at HSPH